All vets from any time in service need to look at this questionnaire posted at the Mefloquine (Lariam) Action Organizations’ website. Download and print the pdf and then fill it in for your own doctor. The way the questions and chart are set up shows medical professionals the wider range of possibilities now proved about the damage — some permanent — that mefloquine causes to your brain and to your body’s main organs. Go here: Side Effects Questionnaire for Canadian and American vets suffering from mefloqouine (Lariam) side effects.
I have also added this organization to the blog roll of references on the right of Homecoming blogs, but when you go to the home page, scroll down the right sidebar to the sections that cover Information and then SUPPORT. Here you will find tips on coping and recovery strategies as well as advice for families of those suffering from mefloquine side effects. BONNIE
See medical paper written by Dr. Remington Nevin and associates re: adverse effects of mefloquine:
Malaria poses a continued threat to U.S. military personnel. At least 423 blood-smear confirmed cases of malaria were diagnosed among members of the U.S. military between January 1st, 2000 and December 31st, 2005; of which at least 64 represent cases attributable to service in Afghanistan . Outbreaks of malaria among U.S. military personnel attributable to service in Afghanistan are well described [1,2], of which infection due to Plasmodium vivax is the principal cause. To protect against the threat of malaria, U.S. military personnel deploying to Afghanistan may be prescribed mefloquine, which must be taken continuously throughout deployments lasting as long as 15 months. Although the long-term use of mefloquine for malaria chemoprophylaxis has historically been considered safe and well-tolerated among civilian travelers [3,4] and deployed military personnel , careful prescribing is needed to minimize the potential for severe neuropsychiatric adverse events, which may include acute psychoses, anxiety, depression, paranoia, myoclonus, and seizures . Although the underlying mechanism of these adverse events is unknown, individuals with certain psychiatric and neurological histories appear to be at highest risk [4,5]. The U.S. package insert cautions that mefloquine “should not be prescribed for prophylaxis in patients with active depression, a recent history of depression, generalized anxiety disorder, psychosis, or schizophrenia or other major psychiatric disorders, or with a history of convulsions” .
To quantify the prevalence of, and identify demographic characteristics associated with contraindications to mefloquine use among deployed U.S. military personnel, a retrospective cohort study was performed using information available in military personnel, medical surveillance [1,4,7], and pharmacosurveillance databases [4,8].